KIND1 Orthologs

Aliases: Kindlin-1, Kindlerin, UNC-112 related protein 1, C20orf42, FERMT1, UNC112A, RP5-1056H1.1, DTGCU2, FLJ20116, FLJ23423, KIND1, URP1

Pfam Domain Structure

From FERMT1 (human)

Members of the KIND1 ortholog set
Human Mouse Rat Chicken Fly Worm
CMKB FERMT1 Fermt1 Fermt1 C20orf42 Fit2 -
Entrez Gene 55612 241639 296179 416727 39907 -
Uniprot FERM1_HUMAN FERM1_MOUSE - - - -
OMIM 607900 - - - - -
Reagents - - - - - -
Results - - - - 1 available -
  1. Dowling JJ, Gibbs E, Russell M, Goldman D, Minarcik J, Golden JA, Feldman EL. Kindlin-2 is an essential component of intercalated discs and is required for vertebrate cardiac structure and function. Circ. Res. 2008; 102:423-31 (PubMed)
  2. Goult BT, Bouaouina M, Harburger DS, Bate N, Patel B, Anthis NJ, Campbell ID, Calderwood DA, Barsukov IL, Roberts GC, Critchley DR. The structure of the N-terminus of kindlin-1: a domain important for alphaiibbeta3 integrin activation. J. Mol. Biol. 2009; 394:944-56 (Full Text)
  3. Herz C, Aumailley M, Schulte C, Schlötzer-Schrehardt U, Bruckner-Tuderman L, Has C. Kindlin-1 is a phosphoprotein involved in regulation of polarity, proliferation, and motility of epidermal keratinocytes. J. Biol. Chem. 2006; 281:36082-90 (PubMed)
  4. Ussar S, Wang HV, Linder S, Fässler R, Moser M. The Kindlins: subcellular localization and expression during murine development. Exp. Cell Res. 2006; 312:3142-51 (PubMed)
Consortium Results & Data
Results & Data
Ortholog Species Type Description Method Status Source Publications
KIND1 none phosphorylation site Kindlin Ectopic expression in HEK cells 4 phospho-sites in 79.4% coverage of 645 aa Parsons
Discovery» Drosophila Morphology Genes
Gene Name Cell Count/
Entrez Gene: 39907
Fermitin 2 9.000
0.935 0.942 Actin: 0.959
Area: 0.964
Ratio: 0.995

How many degrees of interaction?

Legend: Legend for CMKB pathways