MAPK1 Orthologs

Aliases: protein tyrosine kinase ERK2, mitogen-activated protein kinase 1, mitogen-activated protein kinase 2, extracellular signal-regulated kinase 2, ERK, MAPK1, p38, p40, p41, ERK2, ERT1, MAPK2, PRKM1, PRKM2, P42MAPK, p41mapk

Pfam Domain Structure

From MAPK1 (human)

Members of the MAPK1 ortholog set
Human Mouse Rat Chicken Fly Worm
CMKB MAPK1 Mapk1 Mapk1 MAPK1 rl mpk-1
Entrez Gene 5594 26413 116590 373953 3354888 175545
Uniprot MK01_HUMAN MK01_MOUSE MK01_RAT - ERKA_DROME SUR1_CAEEL
OMIM 176948 - - - - -
Reagents - - - - - -
Results 5 available - - - 1 available -
References
  1. Bode AM, Dong Z. The functional contrariety of JNK. Mol. Carcinog. 2007; 46:591-8 (Full Text)
  2. Borsello T, Forloni G. JNK signalling: a possible target to prevent neurodegeneration. Curr. Pharm. Des. 2007; 13:1875-86 (PubMed)
  3. Cook R, Wu CC, Kang YJ, Han J. The role of the p38 pathway in adaptive immunity. Cell. Mol. Immunol. 2007; 4:253-9 (PubMed)
  4. Dominguez C, Powers DA, Tamayo N. p38 MAP kinase inhibitors: many are made, but few are chosen. Curr Opin Drug Discov Devel 2005; 8:421-30 (PubMed)
  5. Meloche S, Pouysségur J. The ERK1/2 mitogen-activated protein kinase pathway as a master regulator of the G1- to S-phase transition. Oncogene 2007; 26:3227-39 (PubMed)
  6. Raman M, Chen W, Cobb MH. Differential regulation and properties of MAPKs. Oncogene 2007; 26:3100-12 (PubMed)
  7. Roberts OL, Holmes K, Müller J, Cross DA, Cross MJ. ERK5 and the regulation of endothelial cell function. Biochem. Soc. Trans. 2009; 37:1254-9 (PubMed)
  8. Roberts PJ, Der CJ. Targeting the Raf-MEK-ERK mitogen-activated protein kinase cascade for the treatment of cancer. Oncogene 2007; 26:3291-310 (PubMed)
  9. Shaul YD, Seger R. The MEK/ERK cascade: from signaling specificity to diverse functions. Biochim. Biophys. Acta 2007; 1773:1213-26 (PubMed)
  10. Stains CI, Luković E, Imperiali B. A p38α-selective chemosensor for use in unfractionated cell lysates. ACS Chem. Biol. 2011; 6:101-5 (Full Text)
  11. Turjanski AG, Vaqué JP, Gutkind JS. MAP kinases and the control of nuclear events. Oncogene 2007; 26:3240-53 (PubMed)
  12. Wang Y. Mitogen-activated protein kinases in heart development and diseases. Circulation 2007; 116:1413-23 (PubMed)
Consortium Results & Data

Internal Server Error

The server encountered an internal error or misconfiguration and was unable to complete your request.

Please contact the server administrator, vvmoti@weizmann.ac.il and inform them of the time the error occurred, and anything you might have done that may have caused the error.

More information about this error may be available in the server error log.


Apache/2.2.15 (Red Hat) Server at www.cellmigration.org Port 80

Internal Server Error

The server encountered an internal error or misconfiguration and was unable to complete your request.

Please contact the server administrator, vvmoti@weizmann.ac.il and inform them of the time the error occurred, and anything you might have done that may have caused the error.

More information about this error may be available in the server error log.


Apache/2.2.15 (Red Hat) Server at www.cellmigration.org Port 80

Internal Server Error

The server encountered an internal error or misconfiguration and was unable to complete your request.

Please contact the server administrator, vvmoti@weizmann.ac.il and inform them of the time the error occurred, and anything you might have done that may have caused the error.

More information about this error may be available in the server error log.


Apache/2.2.15 (Red Hat) Server at www.cellmigration.org Port 80

Internal Server Error

The server encountered an internal error or misconfiguration and was unable to complete your request.

Please contact the server administrator, vvmoti@weizmann.ac.il and inform them of the time the error occurred, and anything you might have done that may have caused the error.

More information about this error may be available in the server error log.


Apache/2.2.15 (Red Hat) Server at www.cellmigration.org Port 80

Internal Server Error

The server encountered an internal error or misconfiguration and was unable to complete your request.

Please contact the server administrator, vvmoti@weizmann.ac.il and inform them of the time the error occurred, and anything you might have done that may have caused the error.

More information about this error may be available in the server error log.


Apache/2.2.15 (Red Hat) Server at www.cellmigration.org Port 80

Internal Server Error

The server encountered an internal error or misconfiguration and was unable to complete your request.

Please contact the server administrator, vvmoti@weizmann.ac.il and inform them of the time the error occurred, and anything you might have done that may have caused the error.

More information about this error may be available in the server error log.


Apache/2.2.15 (Red Hat) Server at www.cellmigration.org Port 80
Consortium Related Products*
Biosensors » activity page
Ortholog Species Name Type Source Publications
MAPK1 none Erk Intramolecular FRET between FPs - CFP-Erk-YFP
-
Sato et al.

* The resources presented here are largely those generated by the Consortium. The sidebar provides public databases that complement Consortium activities. For mice and biosensors, a public database is not available and therefore we have attempted to generate a migration related list for your convenience.

Pathways

How many degrees of interaction?

Update
Legend: Legend for CMKB pathways