MAPK3 Orthologs

Aliases: mitogen-activated protein kinase 3, extracellular signal-related kinase 1, extracellular signal-regulated kinase 1, MGC20180, HS44KDAP, HUMKER1A, ERK1, MAPK3, PRKM3, P44ERK1, P44MAPK

Pfam Domain Structure

From MAPK3 (human)

Members of the MAPK3 ortholog set
Human Mouse Rat Chicken Fly Worm
CMKB MAPK3 Mapk3 Mapk3 - - -
Entrez Gene 5595 26417 50689 - - -
Uniprot MK03_HUMAN MK03_MOUSE MK03_RAT - - -
OMIM 601795 - - - - -
Reagents - - - - - -
Results 4 available 1 available - - - -
References
  1. Bode AM, Dong Z. The functional contrariety of JNK. Mol. Carcinog. 2007; 46:591-8 (Full Text)
  2. Borsello T, Forloni G. JNK signalling: a possible target to prevent neurodegeneration. Curr. Pharm. Des. 2007; 13:1875-86 (PubMed)
  3. Cook R, Wu CC, Kang YJ, Han J. The role of the p38 pathway in adaptive immunity. Cell. Mol. Immunol. 2007; 4:253-9 (PubMed)
  4. Dominguez C, Powers DA, Tamayo N. p38 MAP kinase inhibitors: many are made, but few are chosen. Curr Opin Drug Discov Devel 2005; 8:421-30 (PubMed)
  5. Meloche S, Pouysségur J. The ERK1/2 mitogen-activated protein kinase pathway as a master regulator of the G1- to S-phase transition. Oncogene 2007; 26:3227-39 (PubMed)
  6. Raman M, Chen W, Cobb MH. Differential regulation and properties of MAPKs. Oncogene 2007; 26:3100-12 (PubMed)
  7. Roberts OL, Holmes K, Müller J, Cross DA, Cross MJ. ERK5 and the regulation of endothelial cell function. Biochem. Soc. Trans. 2009; 37:1254-9 (PubMed)
  8. Roberts PJ, Der CJ. Targeting the Raf-MEK-ERK mitogen-activated protein kinase cascade for the treatment of cancer. Oncogene 2007; 26:3291-310 (PubMed)
  9. Shaul YD, Seger R. The MEK/ERK cascade: from signaling specificity to diverse functions. Biochim. Biophys. Acta 2007; 1773:1213-26 (PubMed)
  10. Stains CI, Luković E, Imperiali B. A p38α-selective chemosensor for use in unfractionated cell lysates. ACS Chem. Biol. 2011; 6:101-5 (Full Text)
  11. Turjanski AG, Vaqué JP, Gutkind JS. MAP kinases and the control of nuclear events. Oncogene 2007; 26:3240-53 (PubMed)
  12. Wang Y. Mitogen-activated protein kinases in heart development and diseases. Circulation 2007; 116:1413-23 (PubMed)
Consortium Results & Data

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Internal Server Error

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Apache/2.2.15 (Red Hat) Server at www.cellmigration.org Port 80

Internal Server Error

The server encountered an internal error or misconfiguration and was unable to complete your request.

Please contact the server administrator, vvmoti@weizmann.ac.il and inform them of the time the error occurred, and anything you might have done that may have caused the error.

More information about this error may be available in the server error log.


Apache/2.2.15 (Red Hat) Server at www.cellmigration.org Port 80

Internal Server Error

The server encountered an internal error or misconfiguration and was unable to complete your request.

Please contact the server administrator, vvmoti@weizmann.ac.il and inform them of the time the error occurred, and anything you might have done that may have caused the error.

More information about this error may be available in the server error log.


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Consortium Related Products*
Biosensors » activity page
Ortholog Species Name Type Source Publications
MAPK3 none Erk Chelation-enhanced fluorophore Imperiali
-
MAPK3 none Erk Chelation-enhanced fluorophore Imperiali
-
MAPK3 none Erk Chelation-enhanced fluorophore - Test SOX-based Erk assay in living cells Imperiali
-
MAPK3 none Erk - (Erk2) Affinity reagent for endogenous Erk2 - genetically encode FRET or environmentally sensitive dye Hahn Hodgson et al., Macnevin et al.

* The resources presented here are largely those generated by the Consortium. The sidebar provides public databases that complement Consortium activities. For mice and biosensors, a public database is not available and therefore we have attempted to generate a migration related list for your convenience.