APBB1IP human: amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
Aliases: amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein, proline-rich protein 73, proline rich EVH1 ligand 1, Rap1-interacting adaptor molecule, retinoic acid-responsive proline-rich protein 1, APBB1IP, INAG1, PREL1, RARP1, RIAM
Pfam Domain Structure
From APBB1IP (human)
Protein Overview
| Official Gene Name | APBB1IP (H. sapiens) |
| RefSeq Protein Name | amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein |
| UniProt Gene Symbol | AB1IP_HUMAN |
| UniProt Name | Amyloid beta A4 precursor protein-binding family B member 1-interacting protein |
References
- Jenzora A, Behrendt B, Small JV, Wehland J, Stradal TE. PREL1 provides a link from Ras signalling to the actin cytoskeleton via Ena/VASP proteins. FEBS Lett. 2005; 579:455-63 (PubMed)
- Lafuente E, Boussiotis VA. Rap1 regulation of RIAM and cell adhesion. Meth. Enzymol. 2006; 407:345-58 (PubMed)
- Ménasché G, Kliche S, Chen EJ, Stradal TE, Schraven B, Koretzky G. RIAM links the ADAP/SKAP-55 signaling module to Rap1, facilitating T-cell-receptor-mediated integrin activation. Mol. Cell. Biol. 2007; 27:4070-81 (PubMed)
- Mor A, Dustin ML, Philips MR. Small GTPases and LFA-1 reciprocally modulate adhesion and signaling. Immunol. Rev. 2007; 218:114-25 (PubMed)
Consortium Related Products*
Mice » activity page
| Ortholog | Species | Name | Method | Phenotype | Status | Jax Availability | Source | Publications |
|---|---|---|---|---|---|---|---|---|
| RIAM | human | RIAM | Targeted - floxed | - |
completed - mouse generated, evaluation in process |
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Gertler |
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* The resources presented here are largely those generated by the Consortium. The sidebar provides public databases that complement Consortium activities. For mice and biosensors, a public database is not available and therefore we have attempted to generate a migration related list for your convenience.