Coro1c mouse: coronin, actin binding protein 1C
Aliases: coronin 3, coronin, actin binding protein 1C, coronin 1c, Coro1c, AL022675, AW455561, AW548837, MGC102522
Pfam Domain Structure
From Coro1c (mouse)
Protein Overview
| Official Gene Name | Coro1c (M. musculus) |
| RefSeq Protein Name | coronin, actin binding protein 1C |
| UniProt Gene Symbol | COR1C_MOUSE |
| UniProt Name | Coronin-1C |
References
- Cai L, Marshall TW, Uetrecht AC, Schafer DA, Bear JE. Coronin 1B coordinates Arp2/3 complex and cofilin activities at the leading edge. Cell 2007; 128:915-29 (PubMed)
- Gandhi M, Goode BL. Coronin: the double-edged sword of actin dynamics. Subcell. Biochem. 2008; 48:72-87 (PubMed)
- Rybakin V, Clemen CS. Coronin proteins as multifunctional regulators of the cytoskeleton and membrane trafficking. Bioessays 2005; 27:625-32 (PubMed)
- Uetrecht AC, Bear JE. Coronins: the return of the crown. Trends Cell Biol. 2006; 16:421-6 (PubMed)
- Yan M, Collins RF, Grinstein S, Trimble WS. Coronin-1 function is required for phagosome formation. Mol. Biol. Cell 2005; 16:3077-87 (PubMed)
- Yan M, Di Ciano-Oliveira C, Grinstein S, Trimble WS. Coronin function is required for chemotaxis and phagocytosis in human neutrophils. J. Immunol. 2007; 178:5769-78 (PubMed)
Consortium Results & Data
Discovery» siRNA migration screen using a wound healing approach
| Gene | Description | MCF-10A phenotype | Secondary screen | Wound Image | Morphology | Time-lapse |
|
CORO1C Aliases: HCRNN4, coronin-3 Entrez Gene: 23603 siRNA catalog |
coronin, actin binding protein, 1C mRNA: NM_014325 Library: MAR Classification: cytoskeletal |
Final bin: Discordant SMARTpool bin: No change Avg area: 1.07 Avg Alamar: 1.08 Knockdown %: not done |
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Discovery» siRNA Focal Adhesion Phenotypes
| Gene | Description | High-Res | Montage |
|
CORO1C Aliases: HCRNN4, coronin-3 Entrez Gene: 23603 siRNA catalog |
coronin, actin binding protein, 1C mRNA: NM_014325 Library: MAR |
 Link |
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Proteomics» Table 1. Identification and Quantitation of Proteins from Cell Body (CB) and Pseudopodium (PD) fractions
| IPI | Locus | Description | CB Spectra | CB peptide | PD Spectra | PD peptide | ratio |
| IPI00008453 | CORO1C | CORONIN-1C. | 43 | 23 | 98 | 22 | 2.28 |
Proteomics» Table 2. Proteins in major organelles and subcellular compartments
| IPI | Locus | Description | CB Spectra | PD Spectra | ratio | Location |
| IPI00008453 | CORO1C | CORONIN-1C. | 43 | 98 | 2.28 | cytoskeleton |
Discovery» PyMT invasive data
| Gene | mRNA | Description | Expression Ratio |
|
Coro1c Entrez Gene: 23790 |
mRNA: AW548837 UniGene: Mm.260158 |
Coronin, actin binding protein 1C | 0.13 |